Researchers discover molecular light switch in photoreceptor cells

(Osaka University) Transducin, a protein found inside photoreceptor cells in vertebrate eyes, alters its cellular location in response to changes in light intensity, allowing our eyes to adapt to the changes. Researchers from Osaka University have now identified a protein, Cul3-Klhl18 ubiquitin ligase, that regulates the movement of transducin inside rod photoreceptor cells, thereby controlling photosensitivity. Therapies targeting this protein may help treat light-induced vision damage in degen...